NEPHROLOGY CRITICAL CARE

RIFLE Criteria Station

Acute Kidney Injury (AKI) Severity & Staging HUD

1. Creatinine / GFR Criteria

Baseline / Healthy
Stable renal function Risk (R)
Cr ↑ 1.5x or GFR ↓ 25% Injury (I)
Cr ↑ 2.0x or GFR ↓ 50% Failure (F)
Cr ↑ 3.0x or GFR ↓ 75%

2. Urine Output Criteria

Normal Output
> 0.5 mL/kg/h Risk (R)
< 0.5 mL/kg/h × 6h Injury (I)
< 0.5 mL/kg/h × 12h Failure (F)
< 0.3 mL/kg/h × 24h (Anuria)

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The Clinical Logic of RIFLE Criteria

The RIFLE criteria (Risk, Injury, Failure, Loss, and End-stage kidney disease) were developed to standardize the diagnosis and severity classification of Acute Kidney Injury (AKI). By using a "worst-of" approach between Serum Creatinine levels and Urine Output, it allows ICU clinicians to rapidly stratify renal risk.

Expert FAQs

What if Creatinine and Urine Output show different stages?

Per clinical protocol, you should always choose the more severe stage. For example, if a patient meets "Injury" by Creatinine but only "Risk" by Urine Output, the final RIFLE stage is "Injury."

Dr. Nikhil Mahajan, PT

Clinical ICU Reviewer

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RIFLE Criteria Station

1. Creatinine / GFR Criteria

2. Urine Output Criteria

The Clinical Logic of RIFLE Criteria

Expert FAQs